Department of Behavioral Health and Intellectual disAbility Services

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Xylazine-related wounds are increasingly presenting an addiction medicine and surgical dilemma in people who use drugs. Initially developed as a veterinary sedative, xylazine has been found increasingly added to illicitly manufactured fentanyl, reportedly to extend the duration of fentanyl intoxication. On the street, xylazine-laced fentanyl is known as “tranq,” “tranq dope,” and “zombie drug.” The management of xylazine-associated wounds needs multidisciplinary care. To better understand the scope of this new problem, review the best current evidence, and reach a consensus on best practices to manage xylazine-associated wounds, a formal consensus meeting was held, and the findings are presented here in this current concepts review.

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